Antibody Expression

RAPID EXPRESS ANTIBODY EXPRESSION

Accelerate your antibody discovery and development with Invenra’s rapid antibody expression services. Whether you need small-scale screening in high-throughput formats or larger quantities for validation, we deliver high-quality, purified antibodies in just 8 weeks—with no material caps and flexible licensing options.

RAPID EXPRESS – VALIDATION SCALE

Features:

Inputs: Your antibody sequences
Deliverables:
- Two-step purified mAb or B-Body® Bispecific Abs
- QC analysis of expressed antibodies
Timeline – 8 weeks from DNA construction to antibody shipment
Flexible Scale – Choose 50mL, 200mL or 500mL expression

Process:

Design & Quote – Collaborate with our team to select from our validated mAb or B-Body formats, desired sample quantiy and expression scale
Express & Purify – We prepare DNA constructs, express, and 2-step purify your antibodies for high purity
Analyze & Deliver – Receive QC analyzed Abs — with no retention limits (you receive the entire yield of Ab)

Advantages:

Seamless B-Body Integration– Test bispecifics alongside traditional mAbs
Flexible Formats – Choose from mAb or 1×1 formats
Two Production Scale Options – Select between 50mL, 200mL or 500mL expression scales and all produced antibody is yours
Full Service Production – Invenra manages all aspects of antibody production from DNA ordering, expression, and two-step purification and characterization
Rapid Antibody Availability – Fully purified material is delivered in 8 weeks from DNA construction
Flexible Commercial Licensing Options – Please contact us to discuss pricing and terms

Expressed Antibody Results

High-yield, high-purity B-Body Bispecific Antibody purified by one-step Protein A purification following transient expression CHO cells, demonstrating stability and purity in reducing and nonreducing PAGE.

93% Purity After One Step Protein A Purification
HPLC analysis illustrates the high yield and-purity possible with B-Body® Bispecific antibody expression and one-step purification. Bispecific Ab was transiently expressed in CHO cells and purified by Protein A purification. HPLC analysis provides readouts of yield and purity as well as valuable, predictive insights for analytical development, downstream processing, and formulation optimization.